Topic: Fierce 15

FierceMedTech Fierce 15

FierceMedTech's 2018 Fierce 15

FierceMedTech’s Fierce 15 class of 2018 is aimed at moving the needle and making us reconsider how far we can reach with the means available today.

Spry Health

Spry describes the Loop as the first noninvasive wearable device that provides continuous, beat-to-beat blood pressure measurements outside the hospital, without the use of catheters or calibrating.

Sana Health

Sana Health wants to move away from the use of opioids to treat pain with a smart mask that uses both audio and visual stimulation to place the brain in a relaxation state to treat chronic nerve pain, while measuring variations in heart rate through a forehead sensor.


Profusa is working to capture biochemical data through injectable hydrogel sensors, so that people and their healthcare teams can monitor their health and make decisions in real time.

Potrero Medical

Potrero Medical has been working to fully automate one of the last remaining vital signs collected in the hospital—urine output and the health of the kidney—by gathering data through a sensor-laden update to the 100-year-old indwelling foley catheter.

Pear Therapeutics

Pear Therapeutics aims to develop digital therapeutics that reproduce the changes seen in a patient’s neural circuitry following traditional, face-to-face sessions of cognitive behavioral therapy.

Mindstrong Health

This Takeda-partnered medtech firm with a serious pedigree is going after mental health using mobile phone apps that analyze user habits to passively track cognitive function and mood, with the goal of predicting mental health events.


Mekonos aims to use silicon nanoneedles to deliver genetic payloads directly into the cell using a purely physical, mechanical form factor, with the goal of greatly lowering the cost and time of developing cell therapies.


Invizius aims to cloak the machine from the body by stealing a trick from the bacteria behind pneumonia and meningitis. By coating the device with a layer of proteins similar to the skin of the microbe, they hope to mimic its ability to hide from the human immune system and shield itself from inflammatory responses.