Top bioresearch breakthroughs for 2008

Wired has come up with its closely-watched list of top scientific breakthroughs of the past year, and the life sciences figure prominently on the top-10 countdown.

On the list: A new approach to reprogramming stem cells to avoid a tendency to become cancerous; sequencing the entire genome of a cancer patient; using a bone marrow transplant from an HIV-resistant donor in Germany to eradicate the virus, pointing to gene editing as a possible cure; using a patient's stem cells to grow a new trachea.

The new trachea was number two on the hit parade and earned kudos as the greatest single breakthrough in life sciences. At the top of the list? Finding ice on Mars. But that's another story.

- read the feature in Wired

Suggested Articles

Compass' CD137 agonist cleared large tumors in mice that other I-O agents had failed to treat. It's advancing the drug into phase 1 human trials.

UPMC researchers are planning clinical trials of a COVID-19 vaccine that uses pieces of the virus' spike protein to create immunity.

Treating mice with niacin increased the number of immune cells in glioblastomas, reducing tumor size and extending survival.