Scientists create cheaper versions of anti-HIV molecule

Researchers have overcome one of the chief obstacles to developing a vaginal gel to protect poor women from HIV infection. Scientists at Case Western Reserve University have invented cheaper versions of an anti-HIV molecule known as PSC-Rantes, which prevents viral entry into cells. The development should make cheaper gels available.

"We always felt we had something very promising here," said Dr. Michael Lederman, the director of the Case Center for AIDS Research based at University Hospitals. "We have been effectively dealing with those challenges and resolving them. That is what it takes to develop a strategy. When we started this, no one thought this would make any sense."

- read this report

Suggested Articles

Compass' CD137 agonist cleared large tumors in mice that other I-O agents had failed to treat. It's advancing the drug into phase 1 human trials.

UPMC researchers are planning clinical trials of a COVID-19 vaccine that uses pieces of the virus' spike protein to create immunity.

Treating mice with niacin increased the number of immune cells in glioblastomas, reducing tumor size and extending survival.