Lund researchers develop Alzheimer's-in-a-dish model

Animal models tend to leave a lot to be desired when it comes to Alzheimer's research. As a result, there's been considerable activity in developing an "Alzheimer's-in-a-dish" model, and investigators at Lund University in Sweden say they've been making progress on that front. Håkan Toresson and colleagues say they were able to develop induced neurons that model the disease after starting with fibroblasts taken from skin biopsies of patients diagnosed with the disease. Significantly, the neurons expressed two key proteins widely assumed to be the trigger for the disease: amyloid beta and tau. Release

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