Heart hormones used to cure cancer in mice

Researchers have revealed that the heart is much more than a blood pump. The organ produces hormones that the body requires to lower blood pressure and flush water and salt out of the body. And now scientists have studied four of those hormones that come from the same gene, and concluded they could play a remarkable role in controlling and perhaps even curing cancer.

Using biotech mice programmed to develop pancreatic cancer--a lethal, fast-spreading form of cancer--as well as breast cancer, the hormones cured slightly more than half of the cases of breast cancer and 37 percent of the pancreatic cancers. There was no tumor recurrence and no reported side effects.

"For 350 years, the heart has been thought of simply as a pump," said Dr. David L. Vesely, director of the department of molecular pharmacology and physiology at the University of South Florida's Cardiac Hormone Center, told HealthDay. "But we now know it makes hormones that lower your blood pressure and get rid of salt and water. So, first we took four of them that all come from the same gene, and looked at them in laboratory cell cultures, and found that they essentially eliminated 97 percent of exposed cancer cells within 24 hours."

- read the article from Health Day

Suggested Articles

Compass' CD137 agonist cleared large tumors in mice that other I-O agents had failed to treat. It's advancing the drug into phase 1 human trials.

UPMC researchers are planning clinical trials of a COVID-19 vaccine that uses pieces of the virus' spike protein to create immunity.

Treating mice with niacin increased the number of immune cells in glioblastomas, reducing tumor size and extending survival.