Cannabinoid drug reduces epileptic seizures in hard-to-treat children

In a study involving 162 children and young adults, investigators at UCSF Benioff Children's Hospital San Francisco found that a purified cannabinoid reduced the number of seizures suffered by patients with severe epilepsy. There was a 36.2% reduction in monthly motor seizures among the children taking Epidiolex, which eliminates the psychotropic element in cannabis. Release

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Five Translational Insights Key to a Successful First-in-Human (FIH) Study – Metabolite-Based Biomarker Discovery and Validation

Translational success rates from pre-clinical animal studies to human clinical trials remain frustratingly low. Learn how metabolomics helps you bridge between the theoretical & practical, between the function & actual activity of your drug molecule to get you closer to the phenotype, sooner.