A new study concludes that two enzymes--SIRT3 and SIRT4--play a key role in mitochondria, regulating the aging process. The researchers say that a drop in calorie intake triggers these two enzymes, invigorating mitochondria--which convert nutrients to energy--creating stronger and more efficient cell batteries. The rise of enzymes prevents mitochondria from developing pores in their membranes that allow protein to leech into the rest of the cell, triggering apoptosis, or cell death. Both SIRT3 and SIRT4 are sirtuins, which have become an intense focus for a handful of biotech companies concentrating on the developing of anti-aging therapies. Harvard Medical School's David Sinclair says that he believes that SIRT3 may prove to be the most effective anti-aging enzyme, because it not only protects cells but provides the same benefits as exercise.
- read the article from Scientific American
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