Isis drug achieves Huntington's breakthrough in rodents

Scientists from University of California, San Diego and Isis Pharmaceuticals ($ISIS) were able to reverse the symptoms of Huntington's disease in animals with an experimental drug, according to the North Country Times. Details are published in the journal Neuron. The treatment, made by Carlsbad, CA-based Isis, improved the symptoms of the fatal neurodegenerative illness to a significant point. Rodents in the trial appeared to recover near-normal movement for a long period and also experienced reduced agitation. Significantly, the treatment, which uses Isis' gene-blocking antisense technology, also blocked the Huntington's disease to the point that it allowed the injured neurons to recover, according to the article. If subsequent animal trials also show promise, human testing could begin within a few years. Story

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