Johns Hopkins: Two genes help predict postpartum depression risk

Johns Hopkins scientists believe two genes could serve as reliable epigenetic biomarkers for postpartum depression. Through mouse studies and tests on 52 pregnant women, they believe that TTC9B and HP1BP3 helped predict with an 85% certainty which women would develop postpartum depression. The condition affects 10% to 18% of all new mothers, and as many as 30% to 35% of women who have had diagnosed mood disorders previously, the researchers note. Details are published in the journal Molecular Psychiatry. Story