> The International Study to Predict Optimized Treatment of Depression (i-SPOT-d) is the largest ever study to evaluate characteristics and treatments of depression, and the researchers hope to discover markers to predict response to antidepressants. Press release
> Proteins in a drop of joint fluid could mark osteoarthritis risk. Article
> DNA copy number variations could predict prostate cancer relapse risk. Article
> MDxHealth has launched ConfirmMDx for prostate cancer; an epigenetic test to help identify men who may be able to avoid repeat biopsies. Press release
> Changes in the diameter of blood vessels in the eye look to be a useful pointer to cardiovascular disease in African-Americans with Type 1 diabetes. Article | Abstract
> DNA methylation has potential to diagnose prostate cancer and predict recurrence. Abstract | Press release
> KineMed and CHDI Foundation collaborate to develop new biomarkers of disease progression for Huntington's disease. Press release
> Immune cell activity could mark chronic fatigue syndrome and myalgic encephalomyelitis. Abstract
> A readily available urine dipstick test for protein is an accurate predictor of renal failure in sepsis patients. Press release
> MicroSCALE screening has found genetic modifiers that alter therapeutic responses to treatments in melanoma. Abstract
> Overexpression of a microRNA could point to a poor prognosis in acute leukemia. Press release | Abstract
> Nodal has potential as a prognostic and predictive biomarker in breast cancer. Abstract
> The microRNA miR-181d predicts response to temozolomide in glioblastoma. Abstract
> A 15-gene-expression-profiling (GEP) assay predicts the risk of metastasis in posterior uveal melanomas (eye cancers). Press release | Abstract
And Finally… NCCN Foundation has awarded one of the second series of Young Investigator Awards to Piero Dalerba of Stanford Cancer Institute for evaluation of CDX2 as a predictive biomarker in colon cancer. Press release