Harvard/MIT-developed diagnostic test flagged blood clots in mouse trial

Researchers from U.S. institutions including Harvard University and MIT have developed a urine test that helped spot blood clots during preclinical testing. They attached peptides onto nanomaterials and then injected them into mice. If a blood clot were forming, the peptides got chopped up into fragments, which could be detected in a basic urine test, the researchers said. While more research is needed in both animals and people, the research team said their finding showed that the notion of using synthetic biomarkers to detect vascular disease from urine could have applications down the line in point-of-care diagnostics. Details are published in the journal ACS Nano. Item | Abstract