For glioma, it's all in the letters

Just a single change in one letter in the genetic code could make all the difference when it comes to the outcomes of certain types of glioma. According to a team of U.S. researchers publishing in Nature Genetics, these types of cancer make up around a fifth of all new brain cancers diagnosed annually in the U.S.

Using next-generation sequencing, the researchers found 7 SNPs (single nucleotide polymorphisms; single changes in letters of the code) that could link with types of glioma. One of these was a change from A to G, which increased the chance that the patient had a slower-growing form of the tumor, and a much better chance of survival.

"Being able to tell people that the mass in their brain is this type of tumor is actually good news, because it has a much better prognosis than other brain tumors," says Dr. Robert Jenkins at the Mayo Clinic Cancer Center.

While this is very early-stage research, it could lead to blood tests that determine what subtype of cancer patients with abnormal scans have, ultimately helping doctors decide on the best course of treatment.

- read the press release
- check out the abstract


Like what you're reading?
Click here to get more news delivered to your inbox >>

 

Suggested Articles

AI-based drug molecule designer XtalPi has secured a mammoth funding round totaling $318.8 million, from global banking and tech investors.

LabCorp has licensed a blood test from Genfit designed to identify patients with risky cases of the liver disease NASH.

Philips has launched a compact, single-use device for physically clearing potentially dangerous blood clots lodged in the arms and legs.