First patient gets St. Jude heart valve implant in EU clinical trial; Paulsen pushes for device tax repeal by summer;

 @FierceMedDev: Popular yesterday: GE, NFL to pour $50M into concussion imaging tech. Story | Follow @FierceMedDev

 @MarkHFierce: Becton Dickinson's 2013 Q1 numbers impress. More | Follow @MarkHFierce

 @DamianFierce: Take a look at our list of last year's 10 most important FDA approvals in medical devices and diagnostics. Special Report | Follow @DamianFierce

> St. Jude Medical ($STJ) implanted its new 25 mm-sized Portico transcatheter aortic heart valve into the first patient as part of an ongoing European clinical trial. Release

> Autonomic Technologies says a major new clinical trial shows that  its ATI neurostimulation system successfully helped treat cluster headaches and appeared to reduce their frequency. Release

> Massachusetts startup Alpha Szenszor will work with the Technion-Israel Institute of Technology to commercialize advanced lung cancer diagnostics designed to target human breath. Item

> Minnesota Republican Rep. Eric Paulsen says Congress must repeal the medical device tax by early summer. Story

> IDEV Technologies said it has generated positive 12-month clinical data for its peripheral stent system designed to treat complex atherosclerotic popliteal artery disease. Release

> Allergan ($AGN) reported a nearly 3% increase in medical device net sales during its 2012 fourth quarter. Release

Biotech News

 @FierceBiotech: Popular yesterday on : $ALNY licenses away hot PCSK9 prospect in 'small' $205M deal. Article | Follow @FierceBiotech

@JohnCFierce: This is my weird deal of the week: Merck KGaA gets option on MS therapeutic vaccine. Story | Follow @JohnCFierce

@RyanMFierce: Merck Serono risks short money ($5M upfront) in this MS option deal w/ Opexa. Echoes of Celsion's China pact for ThermoDox. | Follow @RyanMFierce

> Merck execs struggle with growing uncertainty over late-stage R&D. Article

> Left on FDA 'hold,' Idenix hangs up on once-hot hep C drugs. Story

Pharma News

@FiercePharma: Exanatide (Bydureon and Byetta), now sold by BMS/AZ, helped obese teens lose some weight in small study. More | Follow @FiercePharma

@EricPFierce: Ranbaxy plant problems devastate its share of generic Lipitor market. Report | Follow @EricPFierce

@AlisonBFierce: The FDA approved Sun Pharma's generic version of Johnson & Johnson's cancer drug Doxil to end a months-long shortage. News | Follow @AlisonBFierce

> While BMS shops emerging markets brands, GSK wraps $900M buy in India. Report

> Layoffs, check. Now, on to hiring--and talent's scarce. News

> FDA approves generic Doxil to combat drug shortage. Story

Biotech Research News

> New Alzheimer's drug clears amyloid tangles in mice. Item

> Gene discovery could provide relief for deadly staph infections. Report

> New target that stops metastasis could lead to safer cancer therapies. News

> Merck Serono, Feinstein Institute form collaboration to find lupus treatments. Story

Pharma Manufacturing News

> Ranbaxy production glitch devastates its generic Lipitor biz. News

> Aspen to buy Merck API plant in Netherlands to feed expansion. Article

> Ben Venue Bedford plant still missing GMP standards. Story