FDA warns CryoLife over manufacturing problems; CyVek pulls in $5.5M series D for biomarker Dx;

 @FierceMedDev: Swiss team: Nanoscale tissue check boosts breast cancer Dx. More | Follow @FierceMedDev

 @MarkHFierce: GE and the NFL will jointly develop new imaging tech to spot concussions. News | Follow @MarkHFierce

 @DamianFierce: Icon is spending $52M on Cross Country Healthcare's clinical trials business. Report | Follow @DamianFierce

> CryoLife faces an FDA warning for not adequately addressing concerns over its medical device manufacturing and how it handles preservation and distribution of human tissue for cardiac and vascular reconstruction. Story

> Boston remained the top life sciences cluster in 2012, according to an annual Jones Lang LaSalle roundup, followed by San Diego, the San Francisco/Bay Area, Raleigh-Durham and Philadelphia for the top five. Story

> ViewRay, a maker of radiation therapy devices, hired former Accuray COO Chris Raanes as its new president and CEO. Release

> Navidea Biopharmaceuticals ($NAVB) will work with Maimonides Medical Center to explore the use of Lymphoseek in lymphatic mapping procedures for colorectal cancer. Item

> CyVek pulled in $5.5 million in new Series D financing to help commercialize its new CyPlex immunoassay for biomarker analysis in life sciences, drug discovery and clinical research. Item

> Tennessee medical device company Hollywog will be hiring over the next 18 months. The company makes medical devices for pain management and physical rehabilitation. Story

Biotech News

 @FierceBiotech: Popular this weekend: Merck R&D calls for a time-out on osteo blockbuster hopeful. Story | Follow @FierceBiotech

@JohnCFierce: Interesting to see Medicines Co. pay Alnylam $25M upfront for early-stage PCSK9 program. More | Follow @JohnCFierce

@RyanMFierce: $GILD says SVR 67% in oral combo is same as SVR on interferon group in Ph3 FISSION study in hep C types 2&3, meets primary endpoint. Release | Follow @RyanMFierce

> Bitter setback as TB vaccine fails to protect infants in key study. News

> Rockwell shares surge as PhIII iron deficiency study offers upbeat outcomes. Report

> Alnylam licenses away hot PCSK9 prospect in 'small' $205M deal. Story

Pharma News

@FiercePharma: U.S. government finally gets payment rule published. News | Follow @FiercePharma

@EricPFierce: AstraZeneca, Bristol-Myers Squibb create 'Diabetes Inc.,' to give complete attention to diabetes treatment sales. More | Follow @EricPFierce

@AlisonBFierce: A study of the first new TB vaccine in 90 years showed it offered no added benefit to the current vaccine. News | Follow @AlisonBFierce

> Feds grab Shire's attention on Adderall marketing. Report

> Loss of Actos weighs heavily on Takeda. News

CRO News

> Parexel brightens 2013 outlook after strong quarter. Story

> BioClinica eyed for $123M buyout, eventual merger. News

> Indian clinical trials: Private group steps in to increase transparency. More

> Patheon brings bioavailability service to EU with plant expansion. Report

Biotech IT News

> Cypher Genomics chief speaks out from DNA data-crunching crowd. Story

> Clinical trials software player agrees to $123M buyout. News

> Boehringer unleashes iPhone app amid COPD blitz. Report

> Biopharma targets bioinformatics aces in R&D overhaul. Article

Suggested Articles

BD will begin working with Babson Diagnostics to help bring its lab-quality device for collecting blood from capillaries into retail pharmacies.

The former CEO of the molecular testing company Foundation Medicine, Troy Cox, has been named chairman of the Swiss big data firm Sophia Genetics.

Researchers at MIT used a machine-learning algorithm to uncover the potent antibiotic properties hiding within an old small-molecule candidate.