Covidien ponies up for typhoon relief; Med tech VC still flowing in New England;

@FierceMedDev: Solta's aesthetic device sales sag, prompting company to explore selling itself. More | Follow @FierceMedDev

@MarkHFierce: ICYMI: Don't over-promise on what your medical device can deliver. Via BBJ. Story | Follow @MarkHFierce

@MichaelGFierce: ICYMI: Chinese investors pursue groundbreaking med tech from Canada's MDI. Article | Follow @MichaelGFierce

> Covidien ($COV) is donating money and medical supplies to help with disaster relief in the Philippines in the wake of Typhoon Haiyan. Item

> Venture capital investment in medical devices continues its decline nationally, but it is surging to record levels in New England. Story

> NanoString ($NSTG) has won FDA clearance for its nCounter Dx system, launching the analysis platform in the U.S. More

> Israeli startup LapSpace Medical completed a $1 million fundraise to support development of its balloon retractor for laparoscopic surgery. News

Biotech News

@FierceBiotech: GlaxoSmithKline loses its first big PhIII bet on heart drug darapladib. News | Follow @FierceBiotech

@JohnCFierce: Sarepta down 58%--about $700M in market cap vanished. | Follow @JohnCFierce

@DamianFierce: Dendreon slashing about 200 more jobs as Provenge sales slide and buyer interest comes up short. More | Follow @DamianFierce

@EmilyMFierce: New drug target identified for glioblastoma. More | Follow @EmilyMFierce

> Vanda soars after FDA reviewer urges OK for sleep disorder drug. Report

> PsiOxus racks up promising PhII results for cancer-wasting drug. More

Pharma News

@FiercePharma: Breakthrough hep C meds aren't yet for sale, but critics already taking aim at prices. Article | Follow @FiercePharma

@EricPFierce: AstraZeneca thinks there is no place like home for new Zoladex plant. Story | Follow @EricPFierce

@CarlyHFierce: Rare-disease co. ViroPharma finally snatched up after lots of speculation--Shire gets it for $4.2B. Release | Follow @CarlyHFierce

> For-sale Dendreon slashes 150 jobs, cuts more costs in hunker-down move. More

> Embattled Teva settles one thorny problem with $718M Israeli tax deal. News

Pharma Manufacturing News

> AstraZeneca stays in England with $190 million plant. More

> J&J, Amazon fight shows supply-chain weakness in online sales. Story

> Actavis to close NC plant, trim 310 jobs. News

> Daiichi Sankyo says it was burned in Ranbaxy buyout. Article

> Alexion recalls more Soliris. Report

> More than 27M pharma units recalled in Q3. Item

Biotech Research News

> Report proposes revamping Alzheimer's R&D. More

> Japanese fund awards $5.7M in infectious disease vaccine work. Story

> Government shutdown effects on biomedical research outlined. Report

> MacroGenics to receive $9M from Boehringer Ingelheim in preclinical antibody pact. Item

> Compound mimicking gene deletion stops tissue scarring in mice. News

> New drug target identified for glioblastoma. Article

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