Keyword: Opdivo

Combining a checkpoint inhibitor with an anti-TFG-beta drug was effective in mouse models of metastatic prostate cancer, MD Anderson researchers said.

The phase 1/2 results show the efficacy seen at 12 months has persisted, providing early evidence of durable responses.

MacroGenics will kick off a trial later this year that will pit its Incyte-partnered anti-PD-1 drug against Merck’s Keytruda in head and neck cancer.

A phase 1 clinical trial of Ziopharm's IL-12 gene therapy and a production "switch" shows promise in recurrent glioblastoma.

Transplanting T-cells to immunotherapies could lead to better results in non-Hodgkin lymphoma, Mount Sinai scientists have found.

Neon's personalized neoantigen vaccine coupled with Opdivo staved off cancer longer than Opdivo alone in patients with lung, bladder and skin cancer.

Nektar Therapeutics has posted updated data on its NKTR-214-Opdivo cocktail in first-line melanoma that features four more complete responses.

A CD40-activating antibody combined with BMS's Opdivo and chemo shrunk tumors in 20 out of 24 patients with pancreatic cancer.

Bristol-Myers is testing its leukemia therapy Sprycel in a phase 2 combo study with the anti-PD-1 drug Opdivo in non-small cell lung cancer patients.