Keyword: Kyowa Hakko Kirin

Kyowa Kirin manufacturing plant

25. Nourianz

Kyowa Kirin won FDA approval for istradefylline as an add-on treatment for Parkinson’s disease in August, more than 10 years after it was handed a thumbs-down in 2008 and six years after it got its Japanese go-ahead.


In nine years, Ultragenyx grew from two employees to 700, striking partnerships, jumping into gene therapy through its acquisition of Dimension Therapeutics and getting two rare disease drugs to market.