Keyword: Georgetown University Medical Center
Parkinson's patients in a trial of Novartis' Tasigna showed a boost in dopamine that may have halted the decline of motor and non-motor functions.
Kv11.1 channels, which are targeted by Pfizer's anti-arrhythmia drug Tikosyn (dofetilide), are also implicated in PAH, scientists have found.
Based on phase 2 data, a Georgetown University team showed that Tasigna reduces toxic protein clumps and restores dopamine metabolism in Parkinson's.
In mouse models of obesity, the naturally occurring protein FGFBP3 drastically reduced fat mass.
A mouse study and a human population study find chemotherapy might compound cognitive deficits in cancer patients with the APOE4 gene.
Two biotech startups, Oncternal and Tokalas, have unveiled a merger today that will see the pair combine their research efforts on new experimental cancer drugs under one umbrella group.