Vaginal gel flunks HIV prevention trial; Genentech, Galena team on breast cancer trial;

 @FierceBiotech: Onyx Pharma shares soar on report of its hunt for options, acquirers. Story | Follow @FierceBiotech

 @RyanMFierce: Roche inked a deal with PTC for Spinal Muscular Atrophy program, $30M upfront and $460M in biobucks. | Follow @RyanMFierce

 @MaureenFierce: China prepares for big entry into vaccine market. Will be game-changer if China can alleviate safety concerns. Report | Follow @MaureenFierce

> A trial of vaginal gel tenofovir to prevent HIV infection ended in disappointment after data showed that the drug was no more effective than the placebo at preventing disease transmission. Article

> Genentech and Galena Biopharma are teaming up on a Phase II trial of Galena's breast cancer vaccine NeuVax and Genentech's Herceptin. Financial details of the deal were not disclosed. Report

> The FDA has accepted Horizon Pharma for Lodotra, a modified-release formulation of low-dose prednisone, for the treatment of rheumatoid arthritis. Release

Pharma News

 @FiercePharma: Supreme Court agrees to hear sales-rep overtime suit. Ruling promises to affect the whole industry-WSJNews | Follow @FiercePharma

> Ex-PhRMA chief's $11.6M tops among healthcare reform lobbyists. Article

> Eurozone fears have drugmakers re-strategizing. Article

> Facebook yanks URL until Mercks agree who gets it. Report

Biotech Research News

> Neuron implants fix broken brain circuitry in obese mice. News

> Combo drug offers potent weapon against radiation exposure. Story

> Princeton research could speed pharma discoveries. More

> New target discovered in battle against lymphoma. Piece

Manufacturing News

> McKesson, J&J eye GHX platform for e-pedigree. Item

> Hospira to spend $375M in manufacturing upgrades. Report

> Europe takes precautions with Ben Venue drugs. News

> Ranbaxy, FDA near $400M deal on longstanding violations. Story

> McKesson, J&J eye GHX platform for e-pedigree. Article

And Finally... Civitas Therapeutics has secured new funding from The Michael J. Fox Foundation for Parkinson's Research, which will support clinical testing of its inhaled Parkinson's therapy through the proof of concept stage. Article

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