Joint discovery and development of novel small molecule therapies for cancer
Novel cancer targets coming from Servier and Galapagos
Research access payment of €2 million for Galapagos
Milestones for Galapagos could reach €260 million, plus royalties
Servier to develop and commercialize drugs worldwide, Galapagos retains exclusive U.S. rights
Paris, France and Mechelen, Belgium; 3 October 2011 - Servier, a leading French pharmaceutical company, and Galapagos NV (Euronext: GLPG) announced today that they have entered into a multi-year strategic alliance to develop new cancer therapies.
The alliance builds on a combination of novel Galapagos and Servier targets in oncology. Galapagos will be responsible for the discovery and development of new candidate drugs against these targets. Servier will have an exclusive option to license each small molecule program after the completion of pre-clinical development by Galapagos. Upon exercise of each option, Servier will be responsible for further clinical development, registration and commercialization. Galapagos retains exclusive rights for clinical development, registration and commercialization in the United States.
Under the terms of the agreement, Galapagos will receive research access payments of €2 million from Servier. Galapagos is also eligible to receive discovery, development, regulatory and other milestone payments that could reach €260 million, plus royalties upon commercialization of products by Servier.
"Galapagos continues to deliver the innovation that research-based pharma companies are seeking to complement their pipelines. In this new alliance, Servier and Galapagos combine both their oncology targets and their capabilities in cancer drug discovery," said Onno van de Stolpe, CEO of Galapagos. "Similar to our osteoarthritis alliance with Servier, Galapagos retains the U.S. rights, which represents a large potential, considering the unmet medical need in cancer."
"Based on the progress made already in our osteoarthritis collaboration with Galapagos, we are convinced of Galapagos' ability to deliver new cancer drugs based on novel targets. This alliance complements our very innovative cancer pipeline and is in line with Servier's commitment to develop new treatments for sufferers of uncured diseases," said Emmanuel Canet, Head of R&D at Servier.
"We are pleased to start this collaboration in oncology with Galapagos. Combination of our capabilities will allow the accelerated development of new drugs against innovative targets, some of them coming directly from our exploratory research," said Stéphane Depil, MD, PhD, in charge of Oncology R&D at Servier.
Servier Research Group is a privately-run French research based pharmaceutical company with a 2010 turnover of €3.7 billion. Current therapeutic domains for Servier medicines are cardiovascular, metabolic, neurological, psychiatric and bone and joint diseases as well as oncology. Servier is established in 140 countries worldwide with over 20,000 employees. More info at: www.servier.com
Galapagos (Euronext: GLPG; OTC: GLPYY) is a mid-size biotechnology company specialized in the discovery and development of small molecule and antibody therapies with novel modes-of-action. The Company is progressing one of the largest pipelines in biotech, with seven programs in development and over 50 discovery programs. Through risk/reward-sharing alliances with GlaxoSmithKline, Lilly, Janssen Pharmaceutica, Roche and Servier, Galapagos is eligible to receive up to €2.8 billion in downstream milestones, plus royalties. The Galapagos Group has about 800 employees and operates facilities in six countries, with global headquarters in Mechelen, Belgium. More info at: www.glpg.com