Sanofi adds PhIII MS data for teriflunomide; Patheon wins $18M Boehringer contracts; Genzyme vet named CEO at Proteostasis;

@FierceBiotech: Amgen will axe 380 R&D staffers as it trims rising costs. Item | Follow @FierceBiotech

@JohnCFierce: Thanks to Peter Mueller, Doug Williams, Omid Farokhzad, Tom Hughes and Stephen Knight for an interesting conversation on early stage R&D. | Follow @JohnCFierce

> Investigators for Sanofi and its newly acquired unit Genzyme say that new data from its pivotal study of the oral MS drug teriflunomide "significantly reduced annualized rates of relapses leading to hospitalization." Release

> Contract drug manufacturer Patheon says that it has won a pair of contracts worth $18 million to produce experimental diabetes drugs for Boehringer Ingelheim. Story

> Cambridge, MA-based Proteostasis has named Genzyme vet Mark J. Enyedy as its new CEO. Release

> South San Francisco-based Sunesis reports that it has obtained a $25 million tranched loan facility, grabbing $10 million on closing. Release

> Two former investigators at the CRO Lee Research Institute have pleaded guilty to charges of faking data for a clinical trial of an experimental drug from Merck's Schering-Plough. Story

> Sanofi is paying ImmunoGen a $3 million milestone as SAR3419 moves into a mid-stage study for lymphoma. Story

Pharma News

@FiercePharma: DHL, pharma group assess India's hobbled logistics. Report | Follow @FiercePharma

> Vertex CEO positive on Incivek adoption. Item

> Eli Lilly's profits fall 5% in Q3. More

> Report: Abbott prescription med unit could bring $54M. Article

Vaccines News

> GSK malaria vaccine works in major Phase III trial. News

> Study: 40% of cancers stem from viruses. Article

> Hoopika lands $10M for vaccine platform. Story

> Drug has unexpected promise as HIV vaccine. Report

> Twitter opinions linked to vaccine uptake. Item

Manufacturing News

> Rogue online pharmacies try Twitter marketing. Report

> APP taps parent Fresenius' facilities to boost propofol supply. News

> GSK warned over lack of contamination control. Article

> Prevention efforts yield 33% drop in cargo theft. Story

> Hospira plant remediation stings company financials. Piece

> Ben Venue inspection yields 48 GMP violations. Item

And Finally... A new study from the UT Southwestern Medical Center finds that estrogen is a key weight regulator with a "profound" impact on metabolism. Release

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