Plexxikon strikes $100M collaboration pact

Plexxikon and France's Servier have struck a collaboration deal to discover non-peptidic renin inhibitors. Renin is an enzyme known to play a direct role in hypertension, renal failure and vascular disease. Under the terms of the agreement, Plexxikon will receive an upfront payment, research funding, and potential milestone payments totaling over $100 million. Servier will be responsible for clinical development and commercialization of the products and will receive an exclusive worldwide license for any renin inhibitors discovered through the collaboration in the field of cardiovascular disease, including hypertension.

- see the release on the agreement

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