Pfizer has filed an NDA for Sutent, a potent new multi-kinase inhibitor that may have broad uses in the fight against cancer. The drug giant's NDA is focused on gaining FDA approval for Sutent as a tool to fight malignant gastrointestinal stromal tumor and metastatic renal cell carcinoma among patients whose tumors do not respond to or do not tolerate standard treatment options. But researchers believe that the way the drug works -- starving tumors of a supply of blood through a protein inhibitor -- may make it effective against breast, lung, prostate, and colorectal cancers.
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