Medivation wins fast review for enzalutamide at FDA; Pluristem plots orphan drug app;

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> Medivation ($MDVN) and Astellas won a priority review for their closely watched prostate cancer drug enzalutamide, an advance that triggers a $10 million milestone for the biotech company. Shaving months off the review of the treatment is a big plus for the partners, who are planning to elbow into a market that includes Zytiga and Provenge, both relatively new entries. Bayer has been pushing its own candidate, alpharadin. Release

> Pluristem ($PSTI) says it plans to seek an orphan drug approval of its stem cell therapy for aplastic bone marrow. "Orphan drug status in the U.S. would help accelerate our path to full FDA approval and we intend to apply for a similar designation in Europe and global territories," said Zami Aberman, chairman and CEO of Pluristem. Story

> Psyadon Pharmaceuticals announced that its mid-stage study of ecopipam in patients with Tourette Syndrome was stopped early when an interim analysis revealed a statistically significant reduction in the severity of the patients' tic symptoms. Release

> BioCryst ($BCRX) today reported "favorable" 52-week safety results and sustained efficacy from the extension phase of its randomized Phase IIb trial of ulodesine (BCX4208) added to allopurinol in patients with gout who had failed to reach the serum uric acid therapeutic goal of <6 mg/dL on allopurinol alone, as well as positive Phase II safety results in patients with mild to moderate renal impairment. Release

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And Finally… A researcher at the University of North Carolina School of Medicine says that the notorious "bath salts" grabbing headlines act on the brain much the same way as cocaine. Release


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