Ironwood's IBS drug advances in Europe; Nature highlights strategies to improve clinical trials;

@FierceBiotech: Most read on FierceBiotech this week: FDA readies release of long-awaited rules on biosimilars. Story | Follow @FierceBiotech

@ JohnCFierce: I think next year I will do two Fierce 15s, one for Europe, one for the U.S. Follow @JohnCFierce

@RyanMFierce: Geron has new CEO to lead through first-ever US trial of embryonic stem cell therapy. News | Follow @RyanMFierce

@MaureenFierce: Google AdWords ban keeps drug savings from U.S. poor. Article | Follow @MaureenFierce

> Ironwood Pharmaceuticals' ($IRWD) European partner Almirall SA has submitted an application for EU approval of linaclotide, Ironwood's experimental drug for irritable bowel syndrome. Report

> Nature highlighted four strategies to improve clinical trials, providing some expertise from those who have found new ways to advance experimental drugs. Feature

> Bloomberg reported a brutal trend for biotechs on Wall Street: Stock declines among developers with recently approved products. Article

> With the tuberculosis epidemic raging in India, one of the South Asian country's top scientists talks about new drug R&D efforts in the TB field. Item

> The University of Florida showed off the results of an study that said that bioscience companies linked to the university and its graduates have had a $753 million impact on the economy of Alachua County over the past 7 years. Release

> Biogen Idec ($BIIB) Chairman William Young has exercised options and taken in about $1.5 million in the process. Report

> HHS's Biomedical Advanced Research and Development Authority (BARDA) has pumped $56.3 million into the development of 5 treatments against radiation threats. Article

Pharma News

@FiercePharma: AstraZeneca settles Seroquel patent suit, giving Handa license to launch copycat drug in 2016 $AZN #pharma. Report | Follow @FiercePharma

> The trials and tribulations of drug launches. Piece

> AZ settles key Seroquel XR patent case. Story

> Bayer's Xarelto could gain edge from new ACS trial. Article

> Pfizer, Roche, Novartis lead the way in Japan. More

> Report: Schweitzer to step down as AstraZeneca's chairman. Story

And Finally... U.S. scientists have shown that drop in heavy rain in South Asia could be tied to burning fossil fuels. Item

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