Inovio Biomedical Appoints Electroporation Delivery Expert Dr. Iacob Mathiesen to Its Scientific Advisory Board

Inovio Biomedical Appoints Electroporation Delivery Expert Dr. Iacob Mathiesen to Its Scientific Advisory Board
SAN DIEGO, Dec 21, 2009 (BUSINESS WIRE) -- Inovio Biomedical Corporation (NYSE Amex:INO), a leader in DNA vaccine design, development and delivery, announced today that it has appointed Iacob Mathiesen, Ph.D., to its Scientific Advisory Board. Dr. Mathiesen is an international expert in the field of electroporation delivery of biopharmaceuticals including DNA vaccines.
Dr. Mathiesen was previously managing director of Inovio's Norwegian subsidiary, Inovio AS. He received a B.Sc. in Mathematics and Natural Sciences in 1991, an M.Sc. in Mathematics and Natural Sciences in 1993, and a Dr.Philos. in Neurobiology in 1999, all from the University of Oslo, Norway. He is the co-inventor of multiple patents and co-authored numerous scientific papers pertaining to the use of electroporation as a mechanism to safely and significantly enhance the cellular uptake of biological materials and, in the case of DNA-based vaccines, resulting levels of gene expression. His first patent application was the first public disclosure of the use of electroporation to deliver DNA and gene based vaccines to skeletal muscles.

Dr. Mathiesen joins an eminent group of scientific advisors who have and continue to play prominent roles in advancing the fields of vaccines, DNA vaccines and drug delivery, including:

David B. Weiner, Ph.D.
Professor, Dept. of Pathology & Laboratory Medicine, University of Pennsylvania Chairman, Scientific Advisory Board, Inovio Biomedical
Robert S. Langer, Sc.D.
Professor, Chemical and Biomedical Engineering, Massachusetts Institute of Technology
Stanley A. Plotkin, M.D.
Emeritus Professor, Wistar Institute and University of Pennsylvania Consultant, Sanofi Pasteur

Dr. J. Joseph Kim, President and CEO, Inovio Biomedical, stated, "Dr. Mathiesen has pioneered important advancements in the methods, conditions, and devices that are resulting in electroporation becoming one of the most promising - if not the most promising - methods of delivering DNA vaccines. His scientific acumen and leadership will be invaluable as Inovio continues to advance toward its goal of enabling the capabilities of this important new generation of vaccines."

About Inovio Biomedical Corporation

Inovio Biomedical is focused on the design, development, and delivery of a new generation of vaccines, called DNA vaccines, to prevent and treat cancers and infectious diseases. The company's SynCon(TM) technology enables the design of "universal" vaccines capable of protecting against multiple - including newly emergent, unknown - strains of pathogens such as influenza. Inovio's proprietary electroporation-based DNA vaccine delivery technology has been shown by initial human data to safely and significantly increase gene expression and immune responses. Inovio's clinical programs include HPV/cervical cancer (therapeutic) and HIV vaccines. An IND has been filed for an avian influenza vaccine. Inovio is developing its universal and avian influenza vaccines in collaboration with scientists from the University of Pennsylvania, the National Microbiology Laboratory of the Public Health Agency of Canada, and the NIH's Vaccine Research Center. Other partners and collaborators include Merck, Tripep, University of Southampton, National Cancer Institute, and HIV Vaccines Trial Network. More information is available at

This press release contains, in addition to historical information, forward-looking statements. Such statements are based on management's current estimates and expectations and are subject to a number of uncertainties and risks that could cause actual results to differ materially from those described in the forward-looking statements. Inovio is providing this information as of the date of this press release, and expressly disclaims any duty to update information contained in this press release.

Forward-looking statements in this press release include, without limitation, express and implied statements relating to Inovio's business, plans to develop electroporation-based drug and gene delivery technologies and DNA vaccines and pre-clinical and clinical studies. Actual events or results may differ from the expectations set forth herein as a result of a number of risks, uncertainties and other factors, including but not limited to: Inovio has a history of losses; all of Inovio's potential human products are in research and development phases; no revenues have been generated from the sale of any such products, nor are any such revenues expected for at least the next several years; Inovio's product candidates will require significant additional research and development efforts, including extensive preclinical and clinical testing; uncertainties inherent in clinical trials and product development programs, including but not limited to the fact that pre-clinical and clinical results may not be indicative of results achievable in other trials or for other indications, that results from one study may not necessarily be reflected or supported by the results of other similar studies, that results from an animal study may not be indicative of results achievable in human studies, that clinical testing is expensive and can take many years to complete, that the outcome of any clinical trial is uncertain and failure can occur at any time during the clinical trial process, and that Inovio's electroporation technology and DNA vaccines may fail to show the desired safety and efficacy traits in clinical trials; all product candidates that Inovio advances to clinical testing will require regulatory approval prior to commercial use, and will require significant costs for commercialization; the availability of funding; the ability to manufacture vaccine candidates; the availability or potential availability of alternative therapies or treatments for the conditions targeted by Inovio or its collaborators, including alternatives that may be more efficacious or cost-effective than any therapy or treatment that Inovio and its collaborators hope to develop; whether Inovio's proprietary rights are enforceable or defensible or infringe or allegedly infringe on rights of others or can withstand claims of invalidity; and the impact of government healthcare proposals.Readers are also referred to Inovio's Annual Report on Form 10-K for the year ended December 31, 2008 and its Quarterly Report on Form 10-Q for the quarter ended September 30, 2009 filed with the Securities and Exchange Commission which identify important risk factors that could cause actual results to differ from those contained in the forward-looking statements.


SOURCE: Inovio Biomedical Corporation

Inovio Biomedical
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