Shares of Idenix Pharmaceuticals surged this morning after the company reported positive results from a mid-stage study of a combination therapy for the genotype-1 strain of the hepatitis C virus. The triple drug combo included Idenix's lead drug candidate--valopicitabine (NM283)--pegylated interferon and ribavirin compared to pegylated interferon and ribavirin, the standard of care for hep C. The study demonstrated that the drug was well tolerated and produced no pharmacokinetic or pharmacodynamic drug-drug interaction between valopicitabine and ribavirin. That was welcome news to investors, who pushed up the company's stock price by 20 percent in pre-market trading.
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