GSK shutting down a vaccine R&D outpost; Hamburg makes her resignation official;

@FierceBiotech: $PFE's still a likely buyer after its $17B 'hors d'oeuvre.' News | Follow @FierceBiotech

@JohnCFierce: LONDON -- Neil Woodford readies a $300M wager on struggling U.K. Article | Follow @JohnCFierce

@DamianFierce:  Amazing $SNY got Tim and Eric to produce this intentionally awkward earnings video. Video | Follow @DamianFierce

> GlaxoSmithKline ($GSK) is closing a vaccine R&D operation in Montana, planning to lay off 27 workers this year. News

> FDA Commissioner Margaret Hamburg made her impending resignation official, sending a letter to agency staff thanking them for their service. More

> Former Dendreon ($DNDN) CEO Mitchell Gold is at work on a startup called Alpine Immune Sciences, using a $1.3 million investment from his Alpine BioVentures to develop new cancer treatments. Story

Medical Device News

@FierceMedDev: ICYMI: Two new med tech incubators in the works--one with the AMA, the other Georgia Tech. Article | Follow @FierceMedDev

@VarunSaxena2: $PFE exec says $HSP device biz "differentiates them from the competition," giving PFE "new capabilities" & a "new source of revenue growth." | Follow @VarunSaxena2

@EmilyWFierce: Judge overseeing transvaginal mesh cases set to "kick it into high gear" and push for a global settlement More from Reuters | Follow @EmilyWFierce

> Siemens to lay off 7,800 and says healthcare unit 'needs to step up its efforts.' More

> CMS finalizes plan to offer Medicare coverage for CT scans among smokers. News

> FDA approves the first 3D breast CT scanner without tissue compression from Koning. Article

Pharma News

@FiercePharma: Arkansas settles claims it withheld Vertex's Kalydeco on price. More | Follow @FiercePharma

@EricPFierce: UK's #MHRA  closes plant making potentially contaminated globulin component macrophage activating factor. FiercePharmaManufacturing story | Follow @EricPFierce

@CarlyHFierce: Every time I read "lumacaftor," I think of this guy, Lumière. $VRTX #Friday. Picture  | Follow @CarlyHFierce

> Merck KGaA expands diabetes presence in Middle East with new education program. More

> India's Cipla presses court to not honor Novartis Onbrez patent citing Lupin license deal. News

> Hospira may be just the tip of the iceberg for deal-hungry Pfizer. News