EuroBiotech: More Articles of Note

Newspapers

> Genmab posted detailed data from a phase 2a trial of its antibody-drug conjugate tisotumab vedotin in cervical cancer. The expansion cohort data confirm the positive efficacy seen in June’s top-line readout but suggest safety could hold the Seattle Genetics-partnered drug back. About half of the participants suffered from conjunctivitis, prompting Genmab to adopt a risk-management plan part way through the trial. Statement

> Ipsen reported updated data from a trial of cabometyx in first-line renal cell cancer. The readout suggests that, while cabometyx is effective in the indication, it may struggle to beat the efficacy of the combination of Opdivo and Yervoy. Cabometyx is yet to best Pfizer’s Sutent in terms of overall survival in the trial. Release

> NuCana built out its pitch to potential investors in its IPO with data from two trials. In a phase 1b in patients with recurrent ovarian cancer, NuCana’s lead candidate Acelarin in combination with carboplatin yielded an overall response of 39%. NuCana also posted interim data from a phase 1 trial of NUC-3373. Statement I More

FREE DAILY NEWSLETTER

Like this story? Subscribe to FierceBiotech!

Biopharma is a fast-growing world where big ideas come along every day. Our subscribers rely on FierceBiotech as their must-read source for the latest news, analysis and data in the world of biotech and pharma R&D. Sign up today to get biotech news and updates delivered to your inbox and read on the go.

> A phase 3 trial of Advicenne’s ADV7103 met its primary endpoint. The prolonged-release combination of potassium citrate and potassium bicarbonate improved outcomes in patients with distal renal tubular acidosis. Release

> TiGenix bolstered its U.S. team with the appointment of a head of medical department and associate director, clinical project. The new hires come on board at a time when TiGenix is stepping up its interest in the U.S. Statement

> AC Immune wrapped up enrollment in the low-dose cohort of its anti-Abeta vaccine trial. Release

Suggested Articles

Sumitovant CEO Myrtle Potter discusses the $3 billion Roivant-Sumitomo deal, her role at Sumitovant and what's up in 2020.

Antibiotics player Summit Therapeutics is gearing up for a new clinical trial of its lead asset, an antibiotic for Clostridium difficile infection.

In this week's EuroBiotech Report, Roche's risdiplam clears another phase 3 SMA trial, Merck KGaA spinout raises cash and Korean VCs back PDC*line.