EuroBiotech: More Articles of Note


> Shares in Ose Immunotherapeutics crashed after it halted enrollment in a phase 3 trial. Ose hit pause on the trial of Tedopi in non-small cell lung cancer at the request of an independent data monitoring committee. Treatment of patients already enrolled in the trial is continuing. Release 

> Bavarian Nordic posted data from a phase 2 trial of its universal RSV vaccine. The 421-subject trial linked the vaccine to significant increases in antibodies. Bavarian Nordic plans to discuss the data with regulators with a view to running a phase 3 trial during the 2019 to 2020 RSV season. Statement

> A phase 3 trial of remimazolam met its primary endpoint. The trial linked the ultra-short-acting sedative and anesthetic to a significantly higher rate of procedural success than midazolam in patients undergoing bronchoscopy. Germany’s Paion licensed the drug to Switzerland’s Cosmo Pharmaceutical. Cosmo now has the data from two phase 3 trials it needs to file for FDA approval. Release


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> Servier teamed up with Transgene to explore the use of viral vectorization technology in the production of allogeneic CAR-T drugs. The collaboration will make use of Transgene’s viral vector collection. Statement (PDF)

> Heptares entered into two collaborations. The British biotech followed Amgen, Bristol-Myers Squibb, Eli Lilly, Genentech, GlaxoSmithKline, Johnson & Johnson, Merck, Novartis and Sanofi by striking a deal with PeptiDream. One day earlier, Heptares had unveiled a collaboration with the New York University School of Medicine. Release I More

> VarmX raised seed funding. The Dutch biotech will use the cash to fund development of its modified blood coagulation factor X. VarmX thinks the candidate can restore blood clotting in patients taking anticoagulants. Statement

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