Celgene reports positive survival data from multiple myeloma study; EC approves Bayer's Xarelto; Atox reports positive data, plans to raise funds;

Conversations on Twitter :

 @FierceBiotech: GSK's new Promacta approval triggers a spike for Ligand shares. News | Follow @FierceBiotech

 @JohnCFierce: Celgene, Sanofi execs in (another) biopharma insider trading case. Is it that hard for insiders to get away with this? Story | Follow @JohnCFierce

 @RyanMFierce: Rare disease R&D and academic/pharma tie-up trends have melded in Shire's new alliance with Boston Children's. More | Follow @RyanMFierce

> Celgene ($CELG) reports that its experimental cancer drug pomalidomide along with a low dose of a standard therapy significantly extended the lives of late-stage multiple myeloma patients who had failed an average of 5 therapies. Story

> Bayer's oral anticoagulant Xarelto (rivaroxaban) has been approved by the European Commission for the treatment of pulmonary embolism and the prevention of recurrent deep vein thrombosis and PE in adults. Release

> Globes reports that Israel's Atox Bio is out raising funds as it reports positive data from a Phase IIa study of AB103 for necrotizing soft tissue infections. Story

> Eli Lilly ($LLY) has moved up to the #51 slot on the S&P 500, taking Boeing's place on the list. Story

Pharma News

@FiercePharma: New special report for a short week: The world's 20 best-selling generic drugs. Not just the usual suspects. Special Report | Follow @FiercePharma

> Bayer says trumping Reckitt's $1.4B Schiff bid is too rich. Story

> Overnight success proves elusive for oral MS drugs. News

> Sanofi, Celgene execs charged in insider trading ring. Article

Medical Device News

 @FierceMedDev: Spread the word - we're highlighting some of the top M&A targets in devices and diagnostics. Special Report | Follow @FierceMedDev

 @MarkHFierce: Could the device tax lead to supply problems? Item | Follow @MarkHFierce

 @DamianFierce: The SEC says employees of Stryker, Celgene and Sanofi carried on a complex insider trading scam. Report | Follow @DamianFierce

> Push to create pediatric medical devices brings Cincinnati Children's to Israel. Story

> Medtronic sees profit slip despite uptick in revenue. News

And Finally….Investigators at Wake Forest Baptist have been studying whether musical notes can balance brain waves in a new approach to treating insomnia. The technology is being advanced by Brain State Technologies in Scottsdale, AZ. Release