Sirtris Pharmaceuticals is pinning its hopes on resveratrol, a substance in red wine which appears to effect the body much in the same way calorie restriction does. Other companies developing therapies based on calorie restriction include Elixir Pharmaceuticals, BioMarker Pharmaceuticals and LifeGen Technologies. “Some researchers believe antiaging drugs could also improve health in late life--rather than prolong misery--letting people stay in relatively good shape until a swift demise.†Reseachers hope that by delaying the onset of aging, patients will be able to avoid diseases such as cancer, heart disease, Alzheimer's and diabetes. Report (WSJ sub. req.)