Biotech billionaire gains $250M investment for big data play; Struggling Ariad wins a BTD for lung cancer drug;

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@JohnCFierce: Imagine that, $LLY's tabalumab fails for lupus, just like it failed for RA. Release | Follow @JohnCFierce

@DamianFierce: Calithera pulls off an $80M IPO. Release | Follow @DamianFierce

@EmilyMFierce: NIH grants up to $70M to develop new vaccine adjuvants. More from FierceVaccines | Follow @EmilyMFierce

> Biotech billionaire Patrick Soong-Shiong has added a whopping $250 million investment from Kuwait's sovereign wealth fund for NantHealth, which plans to use big data to help transform the way that healthcare is delivered to patients. The company is also adding several execs, including Steve Curd as the new COO. "Our new leadership team has the expertise, relationships and deep knowledge necessary to drive NantHealth forward and make our vision of transforming the healthcare system and delivering truly personalized medicine a reality," said Soon-Shiong in a statement. This new investment brings the company's B round to $320 million. Release

> Shares of the struggling Ariad ($ARIA) got a boost this morning after the Cambridge, MA-based biotech reported that its drug AP26113 won breakthrough drug status at the FDA for ALK-positive non-small cell lung cancer. Shares jumped 9%. Release

> Incyte ($INCY) has scored a $60 million milestone from Novartis ($NVS) related to the reimbursement for Jakavi in Europe. Release

Medical Device News

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@MichaelGFierce: RT @EmilyMFierce: Did you miss our list of notable academic-pharma alliances of 2014? Check it out here. Report from FierceBiotechResearch | Follow @MichaelGFierce

@VarunSaxena2: FDA finalizes cybersecurity guidance in push to secure devices from hackers. Story | Follow @VarunSaxena2

@EmilyWFierce: Gene in monarchs could explain why migratory butterflies are marathoners, rather than sprinters. More from the NYT | Follow @EmilyWFierce

> Boehringer pilots inhalers with sensors to encourage patient adherence. Story

> Philips slapped with $466M verdict in Masimo patent battle. News

Pharma News

@FiercePharma: Our newest special report is live! Check out The top 10 pharma companies by employees. Feature | Follow @FiercePharma

@CarlyHFierce: RT @FiercePharma: Top-read special report Wednesday: The top 10 pharma companies by 2013 revenue. Report | Follow @CarlyHFierce

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Vaccines News

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> NIH grants up to $70M to develop vaccine adjuvants. More

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> Merck Gardasil follow-up could block 90% of cervical cancers--if uptake improves, that is. Article

Pharma Manufacturing News

> Health Canada places import ban on Apotex and IPCA Laboratories. More

> Boehringer to invest a further $19M in German plant expansion. Item

> India sending inspectors on facility visits with global peers. Story

> Officials search for ways to boost output of plant-made Ebola drugs. Article

> PhRMA dealt another legal blow in fight against drug disposal law. Report