Big Pharma rears up to fight CA drug price bill; Vertex advances early-stage CF drugs;

@FierceBiotech: Wyss spins out pathogen-capturing tech into upstart biotech. Story | Follow @FierceBiotech

@JohnCFierce: CDK 4/6 inhibition (no. 2) With FDA 'breakthrough' in hand, Eli Lilly shoots for accelerated abemaciclib OK. Report | Follow @JohnCFierce

> Big Pharma is putting its financial weight behind an effort to defeat a California bill that would restrict drug pricing. More

> Vertex Pharmaceuticals ($VRTX) is planning to advance a pair of next-generation cystic fibrosis treatments into clinical development this fall, looking to test one in tandem with its recently approved combo therapy Orkambi. News

> Wall Street's biotech reticence has slowed the pace of industry IPOs. Story

Medical Device News

@FierceMedDev: ICYMI yesterday: GE Ventures reaffirms commitment to VC with med tech startup program. Article | Follow @FierceMedDev

@VarunSaxena2: #AdvaMed15: CMS has 30 people to evaluate 30,000 diagnostic tests, but more FDA oversight is likely. More | Follow @VarunSaxena2

@EmilyWFierce:  OKs expanded label for InSightec's noninvasive ultrasound fibroid device. News | Follow @EmilyWFierce

> Harvard's Wyss launches Opsonix, backed by Baxter in $8M to get sepsis device into clinic. More

> Study shows UV light-emitting robot reduces hospital-associated infections by 30%. Article

Pharma News

@FiercePharma: Cipla, Serum partner to provide vaccines in S. Africa. More | Follow @FiercePharma

@EricPFierce: Sanofi's Kansas City, MO plant back on the block as its August 2016 closing looms. Story | Follow @EricPFierce

@CarlyHFierce: It's a big day today. Image | Follow @CarlyHFierce

> Oncologists' pricing pushback mounts as docs snub costly me-too drugs. News

> Big Pharma teams up to defeat drug pricing proposal in California. More

Vaccines News

> FDA puts clinical hold on Advaxis' cervical cancer vaccine. More

> Allegheny General Hospital joins Sanofi's Cdiffense PhIII trial. Report

> Cipla, Serum partner to provide vaccines in S. Africa. Story

> Pfizer completes acquisition of two GSK meningitis vaccines. Item

> With PhII data, Genocea's herpes jab continues on blockbuster path, CEO says. Article

CRO News

> WuXi takes its genomics biz to Qatar with new hospital partnership. Report

> Evotec inks a $4.9M deal for oncology R&D. More

> PPD signs a pair of federal deals for battlefield health, flu readiness. Story

> INC bolsters its Phase I platform with new cardiac tech. Item

> Charles River signs a trio of deals in drug discovery. Article

Pharma Manufacturing News

> Cipla moves forward with deal for plant in Algeria. Item

> Investor buys Italian CDMO with plans to roll up others. Report

> Hospira manufacturing mess-up leads to PharMEDium recalls. Story

> Sanofi puts Allegra plant in U.S. back up for sale. Article

Pharma Asia News

> Japan's SymBio partners with Medicines Co. on pain reliever Ionsys. Item

> China gets its due with Nobel, but research problems still remain. Report

> China Biologic subsidiary inks deal to source raw plasma. More

> Singapore's TauRx completes $135M fundraising for PhIII Alzheimer's work. Article

> China's BeiGene snaps up Pfizer executive to run manufacturing ops. Story