Bayer's agnostic R&D spurs novel thinking; Aveo inks a Russian cancer deal;

@FierceBiotech: Baxalta to Shire: The answer is still 'no.' Article | Follow @FierceBiotech

@JohnCFierce: Mystery solved: Star biotech team rallies behind a $36M diabetes spinout from Salk. Article | Follow @JohnCFierce

@DamianFierce: "IPO (n.): An acronym for 'initial public offering' that neglects to mention the taking." More | Follow @DamianFierce

> Bayer's Nimbus Initiative, in which it breaks down barriers between drug, plant and animal R&D, has led to some novel research projects, according to the company's CEO. More

> Aveo Oncology ($AVEO) sold the Eastern European rights to its lead candidate to Russia's Pharmstandard, banking $1.5 million up front with more tied to regulatory and commercial milestones down the line. News

> Australia's Pharmaxis is teaming up with U.K. biotech Synairgen to develop a new treatment for idiopathic pulmonary fibrosis. Item (PDF)

Medical Device News

@FierceMedDev: Mevion moves on from IPO to up to $200M JV backed by China, U.S. investors. Article | Follow @FierceMedDev

@StacyALawrence: Boston Sci ups cardiac monitoring, partners with wearable patch startup Preventice. Story | Follow @StacyALawrence

@VarunSaxena2: IYCMI: Citing cybersecurity concerns, FDA says not to use Hospira infusion pump. Article | Follow @VarunSaxena2

@EmilyWFierce: FDA doubles down on duodenoscope safety with list of cleaning recs. Report | Follow @EmilyWFierce

> Israeli biotech gets $27M to back pivotal trial of gelatin-based GI surgical sealant. News

> Med tech megamergers haven't translated to massive layoffs--at least not yet. Editor's corner

Pharma News

@FiercePharma: Lilly faces first trial over claims of Cymbalta withdrawal symptoms. Report | Follow @FiercePharma

@EricPFierce: FDA may add Baxter saline Mexico plant to U.S. supply. Now if Baxter can just quit having to recall saline. FiercePharmaManufacturing story | Follow @EricPFierce

@CarlyHFierce: ICYMI yesterday: DME data helps Eylea soar in Q2--and poach market share from its Roche rivals. Article | Follow @CarlyHFierce

> Novo Nordisk launches diabetes 'dream team' contest with NBA star as a prize. Item

> With more consolidation on tap in generics, who's next to buy and be bought? Article

> Baxalta to Shire: We're young, we're just starting to grow, and we're rejecting your buyout offer. More

Biotech Research News

> Study IDs a new pathway for drug research into calorie-burning brown fat. Report

> Scripps team finds a drug that fights addiction by eliminating memories. More

> BU researchers identify a new, more precise target for breast cancer. Story

> Virus-like nanoparticle vaccine used to guard against RSV. Item

> Uppsala University points to anti-inflammatory IL-35 as beneficial in pre-clinical Type 1 diabetes. Article

Diagnostics News

> UC Berkeley researchers create faster form of DNA amplification using LED lighting. Article

> NIH study finds blood biomarker for traumatic brain injury using sensitive analyzer. Story

> Foundation Medicine trips in Q2 with sluggish test reimbursement. More

> OraSure gets FDA nod for emergency use of rapid Ebola test. Report

> Illumina sends off first three companies from genomics startup incubator. Article

Pharma Marketing News

> Allergan taps purple-haired millennial mascot for hashtag-heavy women's health push. Story

> CVS creates one-on-one diabetes rivalries with new formulary exclusions. Report

> Pharma leaves ad agencies behind for in-house digital marketing teams. More

> Pfizer nabs rights to Copaxone copycats, setting up head-to-head generics fight with Novartis. Story

> Slam dunk: Novo Nordisk re-signs NBA Hall of Famer for Victoza marketing. Article

Suggested Articles

After delivering a "positive surprise" in December, Biogen is painting a fuller picture of its lupus drug.

A new CRISPR technique neutralizes SARS-CoV-2 by scrambling the virus' genetic code. It could prove useful for fighting other viruses, like influenza.

The deal, which follows a bidding war with AcelRx, gives Melinta another approved antibiotic and potentially complementary R&D expertise.