Applied Proteomics raises $22M, hires CEO; ChemoCentryx prices IPO shares at a discount; CoLucid founder dies;

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@FierceMedDev: Merit Medical discloses warning letter regarding Merit Laureate hydrophilic guidewire. Release | Follow @FierceMedDev

> The diagnostics developer Applied Proteomics has raised $22 million, recruited a new CEO and moved to San Diego. Story

> ChemoCentryx has gone public, pricing 4.5 million shares at $10 each. That's well under the $14 to $16 range the company shot for, offering another example of the difficulties drug developers have with IPOs these days. Story

> James White, the co-founder of CoLucid Pharmaceuticals, has died. White and Art Pappas started the company back in 2005 to develop lasmiditan for acute migraines. Release

@FiercePharma: Can you imagine what Sanofi would look like now if it hadn't bought Genzyme? | Follow @FiercePharma

> Don't look for Lundbeck earnings growth until 2015. Story

> GSK moves European cash to U.K. nightly 'just in case.' Article

> Sanofi CEO: Look out below, profits are falling. Piece

Medical Device News

> Zimmer, ISTO start Phase III study of DeNovo tissue graft. Item

> Siemens teams up with ViiV, Tocagen on companion Dx. Article

> FDA advocates for device 'bar code' in face of OMB delay. More

> Velomedix scores $10.2M in Series B, taps new CEO. News

> Merit, PhotoMedex recipients of FDA warning letters. Piece

Biomarkers News

> Gene signature predicts cancer outcomes. More

> Heart attack? No, it's just a spinning class. Story

> Alzheimer's marker is seen in middle age. Article

> Personalized medicine grows in China with Chinese/Canadian collaboration. News

> Urine biomarker spots aggressive prostate cancer. More

Drug Delivery News

> DexCom, Tandem Diabetes pursue combined CGM/insulin pump. Story

> OptiNose testing nose-to-brain delivery tech with migraine drug. More

> Report: China ramping up for global drug delivery tech battle. Article

> GW's cannabis-based mouth spray gains Austrian OK for MS spasms. News

And Finally... Is exercise the best drug? Penn State investigators say there's a clear connection between exercise and improved levels of enthusiasm and excitement. Release

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