ALSO NOTED: Avandia gets Black Box Warning; Shire licensing deal complete; Pittsburgh companies gain financing; and much more..

> Hang the black crepe: the FDA has ordered new "black box" warning labels for Avandia and its Japanese cousin Actos. FiercePharma

> Schering-Plough has suspended development of a clinical compound for metabolic disease. Report

> Shire's licensing deal for Justiva has become effective. Report

> Pittsburgh Life Sciences Greenhouse has invested $350,000 in three local life sciences companies. Release

> EKR Therapeutics has acquired exclusive marketing and distribution rights to DepoDur (morphine sulfate extended release liposome injection) for the Americas from San Diego-based Pacira Pharmaceuticals. Release

> Caraco Pharmaceutical Laboratories announced a big expansion of its Detroit facilities, creating 600 jobs over the next five years. FiercePharma

> China's pharma market steams ahead. FiercePharma

> In a breakthrough, team of scientists at Oregon Health & Science University's school of medicine has engineered mice that produce human liver cells. FierceBioresearcher

And Finally... Should terminally ill patients be given access to unapproved drugs that have completed only Phase I studies? Poll