Adaptimmune's immunotherapy looks promising in sarcoma; Roche bets on pipeline to endure biosimilar bite;

@FierceBiotech: GSK, Gates Foundation help immuno-oncology player to $56M Series A round. Story | Follow @FierceBiotech

@JohnCFierce: Relentless masochism... NYT story | Follow @JohnCFierce

> Adaptimmune's ($ADAP) T cell therapy charted a 50% response rate in a trial on patients with tough-to-treat synovial sarcomas. More

> Roche ($RHHBY) said its pipeline of innovative drugs has it poised to withstand the coming effect of biosimilar competition for its older products. News

> Genocea Biosciences ($GNCA) has partnered with Memorial Sloan Kettering Cancer Center to identify T cell responses to novel cancer therapies and find new antigen targets. Item

Medical Device News

@FierceMedDev:Dx Digest: Illumina launches $250M share repurchase program; Foundation Medicine stumbles with Q3 earnings miss. Read more | Follow @FierceMedDev

@VarunSaxena2: Investigational drug enables faster absorption of bioresorbable drug-eluting stents. FierceDrugDelivery story | Follow @VarunSaxena2

@EmilyWFierce: Biosensors sells out to Chinese private equity firm for $787M. Story | Follow @EmilyWFierce

> Allergan beefs up in aesthetics with implant purchase. Does M&A suitor Pfizer approve? Report

> Boston Scientific files patent infringement suit against Edwards' Sapien 3 TAVR. Story

> FDA adds another artificial kidney to its Expedited Access Pathway program. News

Pharma News

@FiercePharma: U.S. FDA Form 483 has Indian drugmakers 'spooked'. FiercePharmaAsia story | Follow @FiercePharma

@CarlyHFierce: If the quarterly Vivus trend keeps up, I'm pretty sure that we're about to find out they have zero remaining sales reps | Follow @CarlyHFierce

> Pfizer greatly expands free-drugs assistance as 'stopgap' for struggling patients. More

> Turing promises to cut Daraprim price by year's end, if only partially. News

> Vivus counts $25M in Q3 sales, $300M in debt. How can it possibly cover a $200M-plus Qsymia trial? Article

CRO News

> Icon eyes Asia growth with a pair of exec appointments. More

> Catalent ekes out revenue growth in the face of currency troubles. News

> PRA narrows its sales guidance on the way to a record year. Story

> Charles River boosts its 2015 outlook after strong sales quarter. Article

> WuXi pads its revenue on the way to a big buyout decision. More

Pharma Manufacturing News

> Turing again vows to cut drug's cost as compounder starts manufacturing a version. Story

> India's Torrent Pharma targets production from new plant at U.S., EU. More

> Pfizer will transfer manufacturing tech for Prevenar 13. News

> Novo starts in on massive production buildup. Article

> Novartis, others face higher manufacturing costs with CAR-T cell treatments. More

Pharma Asia News

> Indian drugmakers on the hunt for money and growth. More

> Australia looks to save cash by cutting scripts for common drugs. News

> Generic drugs cut costs by $254B in U.S. last year. Story

> AbbVie nears launch of Viekira into crowded Japan HCV battle. Article

> Roche gets temporary court injunction on Herceptin biosimilar in India. News

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