Takeda's board swept aside concerns over having the company run by a non-Japanese executive, setting up Frenchman Christophe Weber to carry out the plans he believes are needed to turn around the faltering drugmaker.
Christophe Weber is next in line for the throne at Takeda, and the former GlaxoSmithKline exec has a mind to grow the Japanese pharma through dealmaking, hoping to refill the in-transition company's pipeline and expand in emerging markets.
Takeda, Japan's largest drugmaker, has gone through a series of reorganizations in its efforts to take a bigger share of the global market, a process that has included recruiting leadership outside of its native country. That's not sitting very well with some former executives.
CEO Yasuchika Hasegawa's efforts to make Takeda a globally focused company with more international sales has always drawn attention, but the idea that the Japanese company could be run by a "foreigner" has a group of former executives angry and they are letting the board know it.
Takeda is walking away from orteronel, its most advanced oncology candidate, after the prostate cancer treatment failed to significantly improve overall survival in two studies, a setback for the company's in-transition Millennium unit.
Orexigen Therapeutics is on the verge of FDA approval for its obesity drug, after several long years of delay and frustration. But despite its late-to-the-party status--it's the third weight-loss pill in a new generation of treatments--it may end up winning the popularity contest.
If Orexigen wins FDA approval for its new weight loss drug, how will it and its pharma partner Takeda take on the obesity market?
If Orexigen wins FDA approval for its weight loss drug NB32 (which used to be called Contrave) by tomorrow's long-awaited PDUFA date--and the odds are in its favor--look for the biotech and its pharma partner Takeda to barrel into a huge obesity market that has provided a chilly reception for a pair of rivals.
Takeda is finally over the hump with its inflammatory bowel disease drug Entyvio after safety questions threatened its approval. And while the drug will take a backseat to some of the market's heavyweights, some analysts say that won't stop it from hitting the blockbuster mark itself.
After running a gamut of regulatory challenges on vedolizumab's safety profile, Takeda has emerged on the other side with an agency approval to market the drug--as Entyvio--for inflammatory bowel diseases.