Tag:

Oncology

Latest Headlines

Latest Headlines

Immunocore and Lilly strike a risk-sharing deal in oncology R&D

Immunocore has struck another cancer R&D pact with one of the world's top drugmakers, signing a deal with Eli Lilly that'll both bring in short-term revenue and help the biotech build value in its proprietary pipeline.

Roche partners with Roche on 'breakthrough' PD-L1 cancer program

Today, Roche put out the word that their PD-L1 drug MPDL3280A won the FDA's coveted breakthrough therapy designation, potentially putting it on an inside track at the agency, which has been hurrying along new medicines in the pipeline.

AstraZeneca signs up for MD Anderson's 'moon-shot' immuno-oncology project

MD Anderson's popular "moon-shot" immuno-oncology research project has won over another big industry player looking to play catch-up in the hottest race in cancer drug R&D. AstraZeneca's biologics arm, MedImmune, has become the latest Big Pharma player to join a team that has already attracted Pfizer and J&J.

Assessing the crowd effect on biopharma's risky R&D strategy

What should we make of the heavy, some would say unhealthy, concentration of drug R&D in certain hot categories like oncology and inflammation?

Merck loops Pfizer, Amgen and Incyte in on MK-3475 immunotherapy deal spree

At Merck, the already giant-sized hope that its cancer immunotherapy program for the PD-1 drug MK-3475 represents just swelled significantly in importance. Just ahead of its 2013 earnings report Wednesday, the pharma giant announced plans to tie up with a trio of major league biopharma partners to launch a whole new slate of combination studies that could significantly extend its reach in the oncology market.

Novartis advances rival CDK 4/6 cancer drug to Pfizer's palbociclib

One of Pfizer's top late-stage prospects is its cancer drug palbociclib, an oral inhibitor of cyclin-dependent kinases (CDK) 4 and 6 that the FDA put in its first group of therapies awarded their "breakthrough" drug designation. But Pfizer is not the only Big Pharma company to view the CDK 4/6 pathway as a likely goldmine in oncology. Novartis has now started a slate of Phase I studies of LEE011, which its researchers are touting as a best-in-class contender.

Bayer hits the R&D accelerator on late-stage contenders in cancer, cardio

Over the past two years Bayer has snagged an impressive string of key approvals for cancer and cardiovascular drugs--a much better record than many of its larger Big Pharma rivals. And today the pharma player is rolling out i­­­­­ts slate of the next top drug prospects being groomed for late-stage pipeline work.

Roche's new round of lung cancer data keeps spotlight on immunotherapies

Researchers have posted early-stage data demonstrating that Roche's PD-L1 drug MPDL3280A--which takes the blinders off the immune system to spur an attack on cancer--scored a hopeful 26% response rate among a small group of non-small cell lung cancer patients who smoked.

Merck laterals cancer drug to hungry AstraZeneca, focuses on star programs

In the deal AstraZeneca is paying Merck $50 million upfront and a slate of undisclosed milestones to bring in MK-1775, a WEE1 inhibitor that Merck took up because of its potential to spur repeated cell division, offering a new way to destroy cancer cells.

The hottest disease field for biotech startups and M&A might surprise you

Silicon Valley Bank has been crunching the numbers on biotech launches and M&A deals reaching back 8 years, concluding that there's been a recent shift in the disease focus of companies getting funded in Series A rounds, while M&A deals surged over the past two years as upfront payments dwindled.