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First miRNA drug enters human studies

Denmark's Santaris has kicked off a Phase I study of SPC3649, a potential treatment for hepatitis C infection. The trial marks the first time a microRNA drug has been tested in humans. SPC3649 will Read more...
Tags: Hepatitis C   RNAi   Santaris   genes   Phase II  

SPOTLIGHT: Sangamo targets gene manipulation

Forbes has highlighted the development work of Sangamo BioSciences, which has a "hefty" pipeline of drug candidates in development that use zinc-finger DNA binding proteins to manipulate genes for a Read more...

Shares slip as developers see RNAi doubts

Shares of Opko and Alnylam have slid since a new study published in late March concluded that experimental drugs developed with the hot new science of RNA interference may work by activating the Read more...

Osmetech: biomarker license gives it diagnostics edge

Osmetech says its exclusive license for a key biomarker gives the company a big edge in identifying potential adverse reactions to Read more...
Tags: FDA   genes   Warfarin   genetic test  

RNAi screening finds 273 proteins used by HIV

Harvard Medical School's Dr. Stephen J. Elledge and a team of scientists used RNA interference to screen thousands of protein-making genes, and have identified 273 proteins HIV needs in order to Read more...

Genizon pockets $31M CAD in fifth round

Canada's Genizon BioSciences has garnered $31 million Canadian in its fifth round of financing. The lead investor is BTF B.V. of Haarlem, The Netherlands, which specializes in late-stage biotech Read more...
Tags: Pfizer   Canada   biomarkers   genes  

More jaw-dropping scientific advances lay ahead

If the past year saw some incredible gains in biology, next year we should see even more sizeable advances. The sequencing of the human genome is now seven years old, but now we're witnessing new Read more...

Upstart biotech attracts A-list investors

An upstart biotech company focused on developing new therapies targeted at the genetic variations linked to dry age-related macular degeneration has raised $37 million in its first round. New Haven, Read more...

Nobel Prize goes to gene targeting trio

As a child, Mario Capecchi spent four years on the streets in his native Italy, surviving by stealing or begging for food. Today, he's one of three scientists--the other two are Oliver Smithies and Read more...