Tag:
bapineuzumab
Latest Headlines
Latest Headlines
UPDATED: Baxter adds Gammagard to growing roster of PhIII Alzheimer's failures
The long and frustrating search for something--anything--that can treat Alzheimer's or blunt its symptoms ran into yet another Phase III roadblock this morning as Baxter International reported that its Phase III study of the immune-bolstering treatment Gammagard ended in failure.
FDA to Alzheimer's researchers: Time to focus on very early stage patients
There has been growing buzz among Alzheimer's researchers that they need to shift their attention to early-stage patients, whose brains are not yet severely damaged by the disease. The FDA added its voice to the move, offering a new draft guidance today aimed at shooing investigators toward a more realistic goal.
Alzheimer's investigators pick Lilly's sola in big prevention study
Eli Lilly's ($LLY) solanezumab has secured an endorsement from Alzheimer's researchers, who will study the experimental drug as a preventive therapy against the memory-robbing disease in patients before symptoms emerge.
Prominent Alzheimer's investigator resigns university post in wake of insider scandal
Noted neurologist and Alzheimer's investigator Sid Gilman has parted ways with the University of Michigan, just days after he figured prominently in the largest insider trading case ever brought by the SEC.
Our top 5 biotech news stories on the web this year
In what has become a holiday tradition here at FierceBiotech , we're offering readers a look back at our most popular stories of the year. Check it out >>
Tau theory comes center stage in Alzheimer's R&D as amyloid advocates regroup
Alzheimer's research has been dominated for years by the amyloid beta hypothesis: Toxic loads of the protein build up in the brain, blighting its ability to retain memories. Cut amyloid levels, say advocates, and you can delay or prevent the disease.
Report: J&J jettisons 130 jobs after PhIII Alzheimer's misfire
Johnson & Johnson is making deep cuts in an Alzheimer's immunotherapy unit in the aftermath of a colossal Phase III failure of a program to advance bapineuzumab against the memory-stealing disease, Pharmalot reported. And the company's budget ax is falling on a total of 130 jobs, hitting the hardest at an R&D operation in South San Francisco.
The Top Phase III Disasters of 2012
Drug development is a tough business. Sometimes, just when you think you're getting to the pot at the end of the rainbow, you find the trap door one step away. It's not supposed to work that...
The top Phase III disasters in 2012
2012 has seen some of the biggest failures in the history of drug R&D.
Click here to see my top 5 flops of the year >>
Medtronic dangles Alzheimer's drug delivery tech at frustrated pharmas
The medical device company's CNS Drug Delivery chief Lisa Shafer told Bloomberg that Medtronic's approach can give pharma companies the inside track on getting their treatments through the blood-brain barrier, offering a straight shot at the beta amyloid buildup that many have targeted.
