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Astellas Pharma

Latest Headlines

Latest Headlines

Astellas adds to deal spree with expanded $675M-plus Cytokinetics pact

Astellas has capped a string of new drug development deals by upping the ante on its pact with South San Francisco-based Cytokinetics. After handing over a $40 million upfront fee for their original 2013 deal, Astellas has come back with $75 million more in near-term financing and more than $600 million in milestones on the table.

Astellas sinks deeper roots into Cambridge's hot R&D field with $1.2B pact

Just weeks ago Astellas teamed up with Harvard's Constance Cepko on a new program for a degenerative eye disease. Today it inked a deal with Proteostasis Therapeutics that could be worth up to $1.2 billion while getting Dana-Farber investigators to help hunt down new cancer drugs that can inhibit K-Ras.

Japanese companies follow Sanofi's lead in shunning Big Pharma M&A trend

In the midst of an unprecedented dealmaking spree that has produced $139 billion in pharmaceutical mergers this quarter alone, one country has been conspicuously absent: Japan. Even such giants as Astellas Pharma and Takeda Pharmaceutical, which have led M&A runs in Japan in the past, have stayed on the sidelines. Why?

Astellas, Medivation's cancer drug Xtandi scores new upbeat PhIII results

Medivation and Astellas Pharma unveiled final results on primary and secondary efficacy endpoints from their Phase III PREVAIL trial of Xtandi (enzalutamide), showing that the drug delayed tumor growth and prolonged the lives of patients with metastatic prostate cancer who previously have not undergone chemotherapy.

Aveo: Tivozanib doesn't do much for colorectal cancer, either

Aveo Oncology's long-troubled tivozanib is unlikely to meet its primary endpoint in a study on colorectal cancer, the company said, sending the biotech back to the drawing board after a high-profile failure in kidney cancer.

Prostate-cancer prodigy Xtandi shines as pre-chemo treatment

Xtandi has reached a key milestone: success in a Phase III trial eyeing the drug from Medivation and Astellas as a prechemo treatment for advanced prostate cancer.

Cold Spring Harbor Lab names Teri Willey as new BD chief

Teri Willey has stepped in to take over as vice president of business development and technology transfer at Cold Spring Harbor Laboratory.

Astellas bites off $490M deal to develop muscle drugs with Cytokinetics

Cytokinetics is on a roll. After topping off its long-term heart drug development deal with Amgen last week with a $75 million licensing deal covering Japan, the South San Francisco-based biotech is back with a $490 million licensing and discovery deal with Astellas, which is concentrating on muscle weakness and fatigue.

Sights set on Asia, Amgen sets up JV development deal with Astellas

Just a few months after Amgen execs lamented a big Asian gap in their global strategy, the Big Biotech company has joined hands with Astellas to set up a new joint venture in Japan. Amgen is contributing 5 experimental-stage programs to the JV, including their late-stage anti-PCSK9 program for the cholesterol drug AMG-145.

Astellas chops OSI, Perseid ops in global R&D restructuring

Tokyo-based Astellas Pharma is rolling out a major R&D restructuring effort, shuttering facilities at its OSI Pharmaceuticals and Perseid Therapeutics subsidiaries and cutting back its work at the Astellas Research Institute of America to focus solely on CNS diseases.