Daniel V. Santi has resigned as CEO and chairman of Kosan Biosciences. Robert G. Johnson Jr., the company's executive vice president of development and chief medical officer, will serve as interim CEO.

OncoGenex Technologies has appointed Stephen Anderson as CFO and Tom Bailey as a member of the board of directors.

Douglas A. Hamilton has resigned as COO and CFO of Javelin Pharmaceuticals. 

Antares Pharma has named Robert F. Apple senior vice president and CFO. 

NanoBio has named David Peralta vice president and CFO. 

Protein Polymer Technologies announced that president and COO Donald Kaplan, Ph.D., has elected to retire from his positions to pursue other opportunities.

Cylene Pharmaceuticals has named Larry D. Witte, Ph.D., as chief scientific officer.

Millennium Pharmaceuticals announced that Stephen M. Gansler will join the company as senior vice president of human resources.

ImClone Systems has promoted Richard Crowley to senior vice president, biopharmaceutical operations.

PRA International has hired Dr. Cynthia Kirk as vice president, global regulatory affairs.

MIV Therapeutics has hired Vlad Budzynski MD, PhD, as senior scientist in drug research and application.

Anu Wallecha, Ph.D has joined the scientific development team of Advaxis.

GenVec has named Russell P. Wesdyk as vice president of business development and strategic planning.

James J. Carroll has joined Biovest International as general manager of the Biovest Advanced Instrumentation Division. 

Nelson M. Simms has joined the board of directors for Aastrom Biosciences.

Blaine Pharmaceuticals has added David Paragamian to its business advisory board.

Industrial Biotechnology has appointed Gurinder Shahi, M.D., Ph.D., as its new chief technologist and chairman of its scientific advisory board.

OrthoLogic has elected William M. Wardell, M.D., Ph.D., to its board of directors.

John (Jack) L. Armstrong, Jr., CEO and president of Genaera, has been elected to its board of directors. 

Chemokine Therapeutics elected Dr. Mohammad Azab to its board of directors. 

Bradley Pharmaceuticals announced that Leonard S. Jacob, M.D., Ph.D., and William J. Murphy, CPA, have been elected to its board of directors.