Topic: ulcerative colitis

The trial linked ABX464 to improvements in mucosal healing and performance on a symptom scale, leading Abivax to commit to a phase 2b.

Sublimity Therapeutics hired Jesse Hall as chief medical officer, as it looks to move its lead candidate into a phase 2b ulcerative colitis study.

Kinnon, a former Life Technologies VP, has spent most of the past decade running diagnostic businesses Transgenomic and ZyGEM.

The trial linked the JAK1 inhibitor to significant improvements in symptoms, laying the groundwork for further development in psoriatic arthritis.

Provention Bio has filed to raise up to $50 million in an IPO, which will bankroll several clinical programs.

Ferring sees the deal as an R&D acquisition that will keep delivering beyond the "front-runner project."

The oral alpha-4-beta-7 integrin antagonist performed badly enough in the first 65 patients for a committee to rule it would be futile to continue.

Topline data show that Arena's ulcerative colitis candidate, etrasimod, beat out placebo in phase 2.

If successful in further trials, OPRX-106 could mount a challenge in the market for injectable and infused TNF drugs.

Theravance will bring its GI drug through phase 2/3 in Crohn's disease and ulcerative colitis.