Topic: regulatory T cells
Rapt Therapeutics filed to raise up to $75 million in its IPO after postponing an earlier attempt to raise $86 million in August.
Capitalizing on a process the body uses to eliminate overly aggressive T cells could be a new way to treat autoimmune diseases.
The takeover gives Roche control of an anti-CD25 antibody that depleted levels of regulatory T cells in preclinical tests.
Suppressing the YAP protein, known for its role in modulating cell death, may help free up the immune system to fight cancer.
A University of Edinburgh-led team has uncovered a mechanism in MS that prevents regulatory T cells—which prevent autoimmune activity—from developing.
Immatics turned to existing investors and new partner Amgen to put together the round, which brings its total raised to date up toward €200 million.
With some tweaks, a gene therapy delivered to the liver could become a new treatment for multiple sclerosis.
The outlay gives Lilly the rights to a drug designed to treat autoimmune diseases by boosting the number and activity of regulatory T cells.
Massachusetts General Hospital scientists have evidence that a TB vaccine prevents the immune system from attacking normal tissues.
Neuroscientists at Brigham and Women's Hospital were searching for clues to the development of MS when they found an antibody with cancer-fighting properties.