Topic: Huntington disease
Vaccinex filed a $46 million Nasdaq IPO to support its development of antibodies and conjugates targeting neurodegenerative diseases and cancer.
Celgene launched a $60 million collaboration with Skyhawk Therapeutics to develop small molecules targeting RNA mis-splicing in neurological diseases.
EIP Pharma is enrolling a phase 2b trial of neflamapimod, which targets synaptic dysfunction.
Alnylam is gearing up to move RNAi therapies for central nervous system disorders into the clinic.
The small trial linked antisense drug RG6042 to a 40% drop in levels of the mutant protein that drives the neurodegenerative disease.
A Polish team is fine-tuning a Cas9 enzyme that can cut one strand of DNA instead of both strands—potentially providing a safe way to edit out the Huntington's gene.
Biotech discoveries over the past week included new way to harness the lethal power of Huntington’s disease and llama antibodies sans llamas.
BioSensics picked up more than $2.5 million in an NIH grant to develop a remote monitoring device for Huntington disease.
Researchers have used a new version of CRISPR to fix problems in RNA rather than to edit DNA, a promising step for a group of diseases that have no cure.
A phase 3 trial of Teva and Active Biotech’s laquinimod in relapsing-remitting multiple sclerosis (RRMS) missed its primary endpoint.