Topic: HIV-resistant immune cells
HIV mutates to evade immune antibodies that defend against pathogens. A Fred Hutch team has gained new insights into those mutations.
The ability to manipulate genes known to play a role in HIV resistance could help eliminate dormant reservoirs of virus that can resurge at any time.
Two recent advances are focused on using engineered T cells and drug nanocrystals to combat the HIV “reservoirs” that hide in the body and cause the disease to re-emerge.
Doctors in Paris discovered that when they treated an HIV-infected lung cancer patient with Opdivo, reservoirs of the virus shrunk.