Topic: cystic fibrosis

The deal follows two underwhelming clinical trial readouts that suggested the drugs may struggle to compete with Vertex.

Insights into how bacteria hibernate and use metals to evade destruction by antibiotics could be useful in drug development.

Boehringer will work with British academics and Oxford BioMedica to develop an inhaled, lentiviral vector-based gene therapy for cystic fibrosis.

Celtaxsys’ cystic fibrosis drug cleared phase 2 by reducing lung exacerbations, such as heavy coughing episodes that can lead to irreversible damage.

A rare cell type, discovered by two teams and named as "pulmonary ionocyte," appears to help drive cystic fibrosis.

The action prompted Galapagos to review the future of its relationship with AbbVie—and provided a boost to cystic fibrosis rival Vertex. 

Vertex's newly expanded site covers 170,000 square feet, boosting Vertex’s ability to hunt for the next generation of blockbusters.

The IPO will tee Translate up to trial an mRNA candidate designed to enable all cystic fibrosis patients to produce fully functional CTFR proteins.

Vertex says its long-acting version of Kalydeco has been held up by an FDA data request—but analysts think it could be a bigger issue for its rivals.