Drug: Torisel (temsirolimus)
Indication: Renal cell carcinoma
Approval Date: May 30, 2007
Scoop: Torisel is an mTOR inhibitor. In in vitro studies using cancer cells, mTOR inhibition blocked the translation of genes that regulate the cell cycle. Torisel improved median overall survival by 49 percent in Phase III compared to interferon-alpha.